Correlative changes of body condition score and levels of serum alpha1-acid glycoprotein and serum sialic acid in dairy cows with abnormal limb bones

By Mizuno, S. and Ogawa, H. and Sasaki, Y. and Satoh, T. and Shimada, W. and Suzuki, K. and Watanabe, K., Tohoku Journal of Veterinary Clinics, 1997
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Description
Limb abnormalities were examined in 45 Holstein cows from 19 different farms [in Japan?]. 16 cows had sole overgrowth, one had hock inflection, one had hock cellulitis and another had sole ulceration. The remaining 26 cows had combinations of two or more conditions. Sole ulceration was positively correlated with serum levels of sialic acid and body condition score (BCS). BCS was negatively correlated with levels of alpha1-acid glycoprotein and of sialic acid. Serum level of alpha1-acid glycoprotein was positively correlated with that of sialic acid. It is concluded that, of the 4 Holstein abnormalities examined, sole ulceration caused the greatest increases in dolour and levels of alpha1-acid glycoprotein and led to decreased BCS, which was attributed to decreased immunocompetence
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