By Ichijo, T. and Ono, H. and Sato, S. and Suzuki, T., Journal of the Japan Veterinary Medical Association, 2000
Description
Serum concentrations of total and free biotin and biotinidase activity were investigated in dairy cows with sole ulcer, heel erosion and foot rot (interdigital necrobacillosis) using agar-plate biotin bioassay using Lactobacillus plantarum ATCC 8014 and colorimetric biotinidase assay. Serum total biotin concentration was significantly lower in cows with sole ulcer and heel erosion than in healthy cows. Serum free biotin concentration in cows with hoof disorders were similar to those in healthy cows. No significant difference was observed in serum biotinidase activity between cows with hoof disorders and healthy cows. Positive correlations were observed, however, between biotinidase activity and concentrations of total and free biotin. It is suggested that biotin ingestion and biotin synthesis by rumen bacteria in cattle with hoof disorders such as sole ulcer and heel erosion may decrease below normal values
Serum concentrations of total and free biotin and biotinidase activity were investigated in dairy cows with sole ulcer, heel erosion and foot rot (interdigital necrobacillosis) using agar-plate biotin bioassay using Lactobacillus plantarum ATCC 8014 and colorimetric biotinidase assay. Serum total biotin concentration was significantly lower in cows with sole ulcer and heel erosion than in healthy cows. Serum free biotin concentration in cows with hoof disorders were similar to those in healthy cows. No significant difference was observed in serum biotinidase activity between cows with hoof disorders and healthy cows. Positive correlations were observed, however, between biotinidase activity and concentrations of total and free biotin. It is suggested that biotin ingestion and biotin synthesis by rumen bacteria in cattle with hoof disorders such as sole ulcer and heel erosion may decrease below normal values
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