Bovine diarrhoea virus/mucosal disease: clinical findings in 103 calves and heifers

By Braun, U. and Giger, T. and Thur, B. and Weiss, M., Schweizer Archiv fur Tierheilkunde, 1996
Research Paper Web Link / URL:
Description
Clinical findings, in order of frequency, in animals persistently infected with bovine diarrhoea virus, included weight loss, erosions of the oral mucosa, diarrhoea, anorexia and fever. In addition, nasal discharge, lymph node enlargement, erosions of the nose, muzzle and interdigital cleft and bronchopneumonia occurred in less than half of the patients. Crustaceous dermatitis was observed in 3 cases and petechial haemorrhage of the oral mucosa in 2 cases with severe thrombocytopenia. Haemoconcentration, leukocytosis, hyperfibrinogenaemia and azotaemia were the most important haematological findings. The serum antibody titre was negative in 65 of 69 patients, whereas 67 of 69 healthy control animals from the same herd had positive titres. Virus was demonstrated in 32 of 34 blood samples and in all 20 skin biopsy specimens obtained from infected animals
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