Bovine fluorosis I: clinical pathology and investigations into source of fluorine

By Bhalerao, D. P. and Jagadish, S. and Samad, A. and Singh, L. K., Indian Veterinary Journal, 1998
Research Paper Web Link / URL:
Description
In a herd of 165 cows on a government farm in Palghar, Mumbai, 93 (56.4%) developed clinical signs of fluorine poisoning, including general unthriftiness, lameness, reduced milk yield and feed intake, diarrhoea, visible bone exostoses, and dental lesions (discoloration, mottling and brown pigmentation). Values for serum calcium were lower, and those for alkaline phosphatase, aspartate aminotransferase, and fluorine were significantly higher than those in 8 control cows. Severely affected animals had mild microcytic hypochromic anaemia, and mild eosinophilia. Analysis of the feed of the affected animals revealed that the concentrate used had a very high fluoride content (186 mg/kg) compared to that fed to the animals used as controls (28.8 mg/kg)
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